Most Common Denial Codes In Medical Billing

Jan 06, 2025
Medical Billing
Most Common Denial Codes in Medical Billing

As a healthcare provider, you know how important accurate billing is. But did you know that even a small error can lead to major issues?

That's why understanding these errors is important so you can avoid them

According to Premier, healthcare claim denials cost over $20 billion each year. But it’s not just about money—delayed payments and appeals can also affect the care you provide.

Before understanding denial codes, let’s first understand what they are. 

What Are Denial Codes? 

Denial codes are alphanumeric codes given by insurance companies to explain why a claim was denied or not paid. For instance, CO-11 means “Error in Coding,” the most common denial codes in medical billing, while CO-18 stands for “Duplicate Claim.” Understanding these codes can make it easier to fix errors and get paid.

Bar chart showing hospital initial claim denial rate rising from 10.2 percent in 2020 to 11.5 percent in 2023 and 11.8 percent in 2024
Figure 1. Initial claim denials keep climbing. The share of claims denied on first submission rose from 10.2% in 2020 to 11.8% in 2024 across a benchmark of more than 2,000 hospitals. Source: Kodiak Solutions revenue cycle benchmark data, reported May 2025.

Types of Denials in Medical Billing

There are two types of denial:

Hard Denials

Hard denials happen when a claim is permanently rejected, with no chance to resubmit. It happens if the service isn’t covered by the insurance, there's no pre-authorization, or if deadlines are missed. 

Reductions in hard denials can be achieved by updating your billing procedures and ensuring compliance through professional medical billing services.

Soft Denials

Soft denials are temporary and can be fixed. They usually happen because of missing information, small coding errors, or patient eligibility mismatches. Unlike hard denials, you can resolve these by submitting extra documentation or correcting mistakes. 

Top 10 Denial Codes in Medical Billing

Bar chart comparing a 19 percent in-network denial rate with a 37 percent out-of-network denial rate in 2024
Figure 2. Network status matters. In 2024, HealthCare.gov insurers denied 19% of in-network claims but 37% of out-of-network claims. Source: KFF analysis of CMS Transparency in Coverage data, published March 2026.
Horizontal bar chart of in-network denial reasons: 36 percent other, 25 percent administrative, 13 percent excluded service, 9 percent no prior authorisation, 5 percent not medically necessary
Figure 3. Why claims are denied. Administrative reasons and “other” together make up more than half of all in-network denial reasons. Source: KFF analysis of CMS Transparency in Coverage data, 2024 plan year, published March 2026.

1. CO-4: Missing or Incorrect Modifier

If a procedure code doesn’t match the modifier or requires one, your claim might get rejected. 

To avoid this, always keep your codes and modifiers updated. 

If it’s denied, simply correct and resubmit, or contact the payer if it’s still rejected.

2. CO-15: Missing or Invalid Authorization Number

If a procedure needs prior authorization and the authorization number is missing or wrong, the claim will be denied. 

To prevent this, track authorizations through payer portals. 

If the claim is denied, check with the payer for the correct authorization number or apply for retroactive authorization.

3. CO-16: Missing Information

Sometimes one missing detail, like a Social Security number or patient accident date, can lead to a denial. 

So, make sure your team knows what information is required and double-check everything before submission. 

If a claim is denied, correct the missing data and resubmit.

4. CO-18: Duplicate Claim

Denial can also happen if a person submits the same claim twice, whether to the primary and secondary insurance or as an unmarked corrected claim. 

It can be prevented by ensuring claims are only submitted once and checked for duplication. 

If resubmitting a corrected claim, use the proper code to avoid confusion.

5. CO-45: Charge Exceeds Fee Schedule

If the amount charged exceeds the agreed-upon rate between the provider and payer, your claim may be denied. 

It can be prevented by reviewing your fee agreements regularly. 

If it’s denied, you may need to work with the patient on a payment plan.

6. CO-22: Coordination of Benefits

The patient's claim will be rejected if it is submitted to the wrong insurance company, even though they have both primary and secondary insurance. 

Always submit to the primary insurance first, and confirm which insurance is primary. 

If denied, correct the insurance information and resubmit.

7. CO-167: Diagnosis Not Covered

Some diagnoses may not be covered by a payer. 

Make sure your diagnosis codes align with the payer’s requirements. 

If the claim is denied, correct the diagnosis and resubmit.

8. CO-50: Procedure Not Medically Necessary

If the payer doesn’t think a procedure is medically necessary, it can be denied. 

To prevent this, ensure thorough documentation of the patient's condition and treatment.

If denied, submit a clear appeal with additional details to prove the necessity.

9. CO-150: Level of Care Not Justified

This denial indicates that the service provided wasn’t justified based on the submitted medical information. 

To prevent this, ensure your documentation clearly shows why the service is needed. 

If denied, check for discrepancies, collect additional information, and submit an appeal.

10. CO-151: Frequency of Service Not Supported

If a service is provided too frequently or exceeds the allowed frequency, it will be denied. 

Proper documentation to justify the frequency of services is key. 

If denied, collect additional supporting documents and appeal.

The 10 Denial Codes at a Glance

All ten codes in one table, with what each one usually means and the fastest fix. Use it as a quick reference when a remittance advice lands on your desk.

Code Meaning Typical fix
CO-4Missing or incorrect modifierCorrect the modifier and resubmit
CO-15Missing or invalid authorisation numberAttach the valid prior-auth reference
CO-16Missing informationSupply the missing field and resubmit
CO-18Duplicate claimConfirm the original was processed
CO-45Charge exceeds fee scheduleAdjust to the allowed amount
CO-22Coordination of benefitsBill the primary payer first
CO-167Diagnosis not coveredReview coverage or appeal with documentation
CO-50Procedure not medically necessaryAppeal with clinical notes
CO-150Level of care not justifiedDocument medical necessity for the setting
CO-151Frequency of service not supportedCheck frequency limits before resubmission

Fixing these one claim at a time is a treadmill. The better move is to find the pattern behind them — which is what a dedicated denial management service is designed to do.

How to Avoid Claim Denials in Medical Billing

Preventing claim denials is all about following a few key steps. Here’s how you can ensure your claims get paid:

  • Train Your Staff

Proper training is very important. If your team isn't updated with the latest claim filing rules, they might make mistakes that lead to denials and lost revenue. Make sure everyone knows the coverage policies and payment requirements.

  • Verify Insurance Information

Submitting claims to the wrong payer is a common cause of denials. To avoid this, check a patient’s benefits eligibility before their appointment. This will confirm their coverage and clarify their financial responsibility upfront.

  • Check Eligibility

Make sure to confirm eligibility for services before treatment. Not all procedures are covered by every insurance plan, so it’s essential to double-check whether a service is covered before submitting a claim.

  • Run Audits

Rather than letting mistakes grow, run regular audits to identify patterns of denials. This helps you fix recurring issues and prevent them in the future.

Horizontal bar chart showing fewer than 1 percent of denied claims are appealed and 66 percent of appeals upheld the denial
Figure 4. The silent leak. Of roughly 85 million in-network claims denied in 2024, fewer than 1% were appealed — and when they were, insurers upheld 66% of those decisions. Source: KFF analysis of CMS Transparency in Coverage data, 2024 plan year, published March 2026.

Talk To Our Billing Team

Our Approach to Denial Management

Denial management in medical billing can be challenging. It requires technical expertise and the ability to effectively communicate with insurance companies to find the best solution.

At our company, we take the hassle out of it. We offer expert medical billing services with a focus on efficient denial management. We combine data-driven processes with a persistent approach to reduce denials and improve your cash flow.

If you’re looking for a reliable partner to manage your billing and reduce denials, reach out to us today!

Explore Denial Management Services →

Conclusion

Medical billing mistakes can be stressful and expensive for healthcare providers. One of the biggest reasons for these errors is denial codes. Understanding these codes and why they happen is key to avoiding them and making your billing process easier.

What Are Claim Denials?

Claim denials happen when an insurance company refuses to pay for healthcare services that a patient receives from a healthcare provider. This can occur for several reasons, such as errors in the claim or issues with the patient’s coverage.

What is the common rejection in medical billing?

One of the most common reasons for claim rejections in medical billing is submitting duplicate claims.

What is the main denial in medical billing?

A common reason for claim denials is missing or incorrect patient information. Errors such as the wrong date of birth, misspelled names, or invalid insurance details can prevent claims from being processed successfully.

What is the most frequent medical error?

Among medical errors, medication errors are among the most common. These can include prescribing the wrong medication, incorrect dosages, or overlooking potential drug interactions, all of which can have serious consequences for patients.

What is the most common cause of 70% of serious medical errors?

Communication problems are a leading cause of serious medical errors, accounting for nearly 70% of such incidents. Miscommunication between healthcare providers or between providers and patients can lead to misunderstandings, delayed treatments, or incorrect procedures.

 

Frequently Asked Questions

What are the most common denial codes in medical billing?

The most common denial codes in medical billing include CO-16 (claim lacks information), CO-11 (diagnosis inconsistent with the procedure), CO-97 (the benefit is included in another service), CO-45 (the charge exceeds the fee schedule), CO-50 (not deemed a medical necessity) and CO-29 (the filing time limit has expired).

What does denial code CO-16 mean?

CO-16 means the claim or service lacks information the payer needs to adjudicate it. It is one of the most frequent denials and usually requires a corrected claim with the missing data, such as a modifier, NDC number or prior authorization.

What is the difference between CO and PR denial codes?

CO (Contractual Obligation) codes mean the provider is financially responsible and the amount cannot be billed to the patient. PR (Patient Responsibility) codes mean the balance may be billed to the patient, for example a deductible, coinsurance or a non-covered service.

How can I reduce claim denials?

Reduce denials by verifying eligibility and benefits up front, checking coding accuracy before submission, scrubbing claims for missing data, and working denials quickly inside payer appeal windows. Our denial management services handle this end to end.

What is denial management in medical billing?

Denial management is the process of identifying, correcting, appealing and preventing denied claims. Done well it recovers revenue that would otherwise be written off and feeds patterns back into front-end processes to stop repeat denials.

About the Author

Qaiser Akash Khan

Co-Founder & CEO, Dilijent Systems, LLC

Qaiser Akash Khan is the Co-Founder and CEO of Dilijent Systems, LLC, a trusted name in Revenue Cycle Management (RCM) for healthcare providers. With years of experience, Qaiser is passionate about creating strategies that increase revenue, reduce denials, and improve operations. His innovative mindset and commitment to staying at the forefront of industry trends and technology help healthcare organizations achieve financial stability while prioritizing quality patient care.

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